Theranostics · 2024 · 12 citations · 2 references
MedicineOncologyRadiation OncologyMitochondrial BiologyRadiation BiophysicsRadiobiologyAlpha-particle TherapyBiological Effects Of RadiationMitochondrial DysfunctionMitochondrial ToxicityParticle TherapyRadiation TherapyApoptosis After IrradiationMitochondrial InvolvementMitochondrial PathwaysMitochondrial ResponseMitochondrial Toxicity MechanismsMitochondrial-associated Membrane Lipid TransferRadiobiological Response
Pb and, more importantly, elucidates the role of damaged mitochondrial transfer in alpha-particle RIBE. These findings provide a novel theoretical mechanism for the antitumor effects of alpha-particles and expand the clinical application prospects of TAT.
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