Concepedia

Diversity-oriented chiral phosphoric acid catalyzed alkylation of indolizines with aminals

Ahmad F. Kassir, Nazar Rad, Patryk Klochowicz, Jarosław M. Granda

Organic Chemistry Frontiers · 2024 · 10 citations · 29 references

DOI

Abstract

This study introduces enantioselective indolizine alkylation with aminals via chiral phosphoric acid catalysis, featuring scalable, functional group-tolerant processes, enabling access to diverse C1/C3-alkylated indolizines.

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