Publication | Open Access
Microglial priming by <scp>IFN</scp>‐γ involves <scp>STAT1</scp>‐mediated activation of the <scp>NLRP3</scp> inflammasome
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Citations
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References
2024
Year
IFN-γ primes microglia by activating STAT1, which upregulates genes that activate the NLRP3 inflammasome. Inhibiting the IFN-γ/STAT1 axis may be a way to treat neurodegenerative diseases and psychiatric disorders that involve microglial priming.
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