GDF11 promotes osteogenic/odontogenic differentiation of dental pulp stem cells to accelerate dentin restoration via modulating SIRT3/FOXO3-mediated mitophagy

SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage

Anne H.-H. Tseng, Shyan-Shu Shieh, Danny Ling Wang · Free Radical Biology and Medicine · 2013 · 445 citations

Life Sciences, Biochemistry, Cell Biology +12

CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma

Jingyue Yao, Jubo Wang, Ye Xu et al. · Autophagy · 2021 · 258 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +14

SIRT3 consolidates heterochromatin and counteracts senescence

Zhiqing Diao, Qianzhao Ji, Zeming Wu et al. · Nucleic Acids Research · 2021 · 164 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy

Jingui Hu, Tao Liu, Fei Fu et al. · Journal of Translational Medicine · 2022 · 120 citations · Full text

Life Sciences, Cardiology, Physiology +17

Induction of dental pulp stem cell differentiation into odontoblasts by electroporation-mediated gene delivery of growth/differentiation factor 11 (Gdf11)

M Nakashima, K Mizunuma, T. Murakami et al. · Gene Therapy · 2002 · 115 citations

Dentistry, Developmental Biology, Oral Biology +16