<scp>KA</scp>‐mediated excitotoxicity induces neuronal ferroptosis through activation of ferritinophagy

Abstract

KA-induced excitotoxicity activates ferritinophagy, and targeting ferritinophagy effectively inhibits downstream ferroptosis. Interference with NCOA4 effectively attenuates KA-induced neuronal damage. This study provides a potential therapeutic target for excitotoxicity related disease conditions.