Early B lymphocyte subsets in blood predict prognosis in sepsis

Abstract

Our study revealed that deficiencies of B, Tr B, and CD5⁺ B cells, as well as a persistent increase in the proportion of DN B cells, were associated with poor prognosis-and that B cell subsets showed predictive value to mortality. These results provide new insights into the roles of B cell subsets in sepsis, as well as ways to better manage its progression and predict its course.