Concepedia

First Results of NURE-Combo: A Phase II Study of Neoadjuvant Nivolumab and Nab-Paclitaxel, Followed by Postsurgical Adjuvant Nivolumab, for Muscle-Invasive Bladder Cancer

Chiara Mercinelli, Marco Moschini, Antonio Cigliola, Benedetta Mattorre, Valentina Tateo, Giuseppe Basile, Laura Lucia Cogrossi, Brigida Anna Maiorano, D. Patanè, Daniele Raggi,

Journal of Clinical Oncology · 2024 · 13 citations · 35 references

DOI

Abstract

To our knowledge, the first results from NURE-Combo trial suggest that this combination could expand the therapeutic opportunities of immune-chemotherapy in patients with MIBC.

References

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Adjuvant Nivolumab versus Placebo in Muscle-Invasive Urothelial Carcinoma

Dean F. Bajorin, J. Alfred Witjes, Jürgen E. Gschwend et al. · New England Journal of Medicine · 2021 · 968 citations · Full text

Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study

Andrea Necchi, Andrea Anichini, Daniele Raggi et al. · Journal of Clinical Oncology · 2018 · 712 citations