Colchicine prevents accelerated atherosclerosis in <i>TET2</i>-mutant clonal haematopoiesis

Abstract

These results highlight the potential value of colchicine to mitigate the higher cardiovascular risk of carriers of somatic TET2 mutations in blood cells. These observations set the basis for the development of clinical trials that evaluate the efficacy of precision medicine approaches tailored to the effects of specific mutations linked to CH.