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PUNCH CD3-OLS: A Phase 3 Prospective Observational Cohort Study to Evaluate the Safety and Efficacy of Fecal Microbiota, Live-jslm (REBYOTA) in Adults With Recurrent <i>Clostridioides difficile</i> Infection

Paul Feuerstadt, Teena Chopra, W Knapple, Nicholas W. Van Hise, Erik R. Dubberke, Brian Baggott, Beth Guthmueller, Lindy Bancke, Michael Gamborg, Theodore S. Steiner,

Clinical Infectious Diseases · 2024 · 24 citations · 8 references

DOIFull text

Open access

Abstract

NCT03931941.

References

8

Changes in Prevalence of Health Care–Associated Infections in U.S. Hospitals

Shelley S. Magill, Erin O’Leary, Sarah J. Janelle et al. · New England Journal of Medicine · 2018 · 1.2K citations · Full text

ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections

Colleen Kelly, Monika Fischer, Jessica R. Allegretti et al. · The American Journal of Gastroenterology · 2021 · 501 citations · Full text

, , +14

Intestinal Dysbiosis and Depletion of Butyrogenic Bacteria in Clostridium difficile Infection and Nosocomial Diarrhea

Vijay C. Antharam, Eric C. Li, Arif Ishmael et al. · Journal of Clinical Microbiology · 2013 · 482 citations · Full text

, , +14

Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double-Blind, Placebo-Controlled Trial with a Bayesian Primary Analysis for the Prevention of Recurrent Clostridioides difficile Infection

Sahil Khanna, Maha Assi, Christine Lee et al. · Drugs · 2022 · 242 citations · Full text

Safety and Durability of RBX2660 (Microbiota Suspension) for Recurrent<i>Clostridium difficile</i>Infection: Results of the PUNCH CD Study

Robert Orenstein · Clinical Infectious Diseases · 2015 · 188 citations · Full text