Short-chain fatty acids reverses gut microbiota dysbiosis-promoted progression of glioblastoma by up-regulating M1 polarization in the tumor microenvironment

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

Pamela V. Chang, Liming Hao, Stefan Offermanns et al. · Proceedings of the National Academy of Sciences · 2014 · 2.1K citations · Full text

Life Sciences, Immunology, Microbiology +17

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment

Qianghu Wang, Baoli Hu, Xin Hu et al. · Cancer Cell · 2017 · 2.1K citations · Full text

Life Sciences, Immunology, Oncology +16

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

Abhishek Jha, Stanley Ching‐Cheng Huang, Alexey Sergushichev et al. · Immunity · 2015 · 2K citations · Full text

Life Sciences, Molecular Biology, Systems Biology +17

Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells

Chi Ma, Miaojun Han, Bernd Heinrich et al. · Science · 2018 · 1.5K citations

Life Sciences, Immunology, Oncology +17

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

Dylan Dodd, Matthew H. Spitzer, William Van Treuren et al. · Nature · 2017 · 1.4K citations

Life Sciences, Biochemistry, Microbiology +14