Pharmacologic Inhibition of EIF4A Blocks NRF2 Synthesis to Prevent Osteosarcoma Metastasis - Concepedia

Concepedia

Publication | Open Access

Pharmacologic Inhibition of EIF4A Blocks NRF2 Synthesis to Prevent Osteosarcoma Metastasis

DOI Full Paper Access

10

Citations

59

References

2024

Year

Michael M. Lizardo, Christopher S. Hughes, Yue Z. Huang, Taras Shyp, Alberto Delaidelli, Hai‐Feng Zhang, Sol Snir Shaool, Annalena F. Renner, Fares Burwag, Leanne C. Sayles,

Clinical Cancer Research

Abstract

Collectively, our data reveal that pharmacologic targeting of EIF4A1 is highly effective in blocking OS metastasis by blunting the NRF2 antioxidant response.

References

	Year	Citations

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