Deuterium Metabolic Imaging of Alzheimer Disease at 3-T Magnetic Field Strength: A Pilot Case-Control Study

Alixander S. Khan, Katie A. Peterson, Orsolya Vittay, Mary A. McLean, Joshua Kaggie, John T. O’Brien, James B. Rowe, Ferdia A. Gallagher, Tomasz Matys

Radiology · 2024 · 19 citations · 22 references

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Abstract

= .04), suggesting an impairment of oxidative glucose metabolism in AD. However, there was no evidence of localization of these changes to the expected regions of metabolic impairment at MRSI, presumably due to insufficient spatial resolution. Conclusion DMI at 3 T demonstrated impairment of oxidative glucose metabolism in the brains of patients with AD but no evidence of regional signal differences. © RSNA, 2024

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