Trends in Genetics · 2024 · 11 citations · 10 references
Life SciencesBioinformaticsGeneticsGenomicsMolecular EvolutionSpeciationEvolutionGenome TopologyPhylogenomic AnalysisSpeciation GenomicsStructural GenomicsThree-dimensional Genome OrganizationComparative Structural GenomicsEvolutionary Structural BiologyGenome Architecture EvolutionStructure-based PhylogenyThree-dimensional Structural Modeling
Genomic information is folded in a three-dimensional (3D) structure, a rarely explored evolutionary driver of speciation. Technological advances now enable the study of 3D genome structures (3DGSs) across the Tree of Life. At the onset of 3D speciation genomics, we discuss the putative roles of 3DGSs in speciation.
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3D genome organization contributes to genome instability at fragile sites
Dan Sarni, Takayo Sasaki, Michal Irony Tur-Sinai et al. · Nature Communications · 2020 · 74 citations · Full text