Concepedia

Ferrostatin-1 inhibits fibroblast fibrosis in keloid by inhibiting ferroptosis

Yang Liu, Xiuli Li, Yanli Wang

PeerJ · 2024 · 19 citations · 16 references

DOIFull text

Open access

Abstract

Ferroptosis exists in keloid. Ferrostatin-1 restrained ECM deposition and fibrosis in keloid through inhibiting ferroptosis, and erastin induced ECM deposition and fibrosis through intensifying ferroptosis.

References

16

Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis

Yingying Yu, Li Jiang, Hao Wang et al. · Blood · 2020 · 567 citations · Full text

The Most Current Algorithms for the Treatment and Prevention of Hypertrophic Scars and Keloids: A 2020 Update of the Algorithms Published 10 Years Ago

Plastic & Reconstructive Surgery · 2021 · 304 citations · Full text

PRMT4 promotes ferroptosis to aggravate doxorubicin-induced cardiomyopathy via inhibition of the Nrf2/GPX4 pathway

Yilong Wang, Shu Yan, Xuemei Liu et al. · Cell Death and Differentiation · 2022 · 288 citations · Full text

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SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis

Lei Feng, Kaikai Zhao, Liangchao Sun et al. · Journal of Translational Medicine · 2021 · 260 citations · Full text

Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis

Aimin Wu, Bin Feng, Jie Yu et al. · Redox Biology · 2021 · 248 citations · Full text