Injectable photocrosslinkable acellular cartilage matrix hydrogel loaded with exosomes for promoting growth plate injury repair

MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity

Shipin Zhang, S. Chuah, Ruenn Chai Lai et al. · Biomaterials · 2017 · 951 citations

Life Sciences, Cell Biology, Immunology +14

Exosomes derived from miR-140-5p-overexpressing human synovial mesenchymal stem cells enhance cartilage tissue regeneration and prevent osteoarthritis of the knee in a rat model

Shi‐Cong Tao, Ting Yuan, Yue-Lei Zhang et al. · Theranostics · 2016 · 724 citations · Full text

Medicine, Cell Biology, Orthopaedic Surgery +17

Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration

Shipin Zhang, Wern Cui Chu, Ruenn Chai Lai et al. · Osteoarthritis and Cartilage · 2016 · 683 citations · Full text

Medicine, Orthopaedic Surgery, Surgery +17

Exosomes derived from miR-92a-3p-overexpressing human mesenchymal stem cells enhance chondrogenesis and suppress cartilage degradation via targeting WNT5A

Guping Mao, Ziji Zhang, Shu Hu et al. · Stem Cell Research & Therapy · 2018 · 476 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Cartilage Regeneration in Osteoarthritic Patients by a Composite of Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Hyaluronate Hydrogel: Results from a Clinical Trial for Safety and Proof-of-Concept with 7 Years of Extended Follow-Up

Yong‐Beom Park, Chul‐Won Ha, Choong‐Hee Lee et al. · Stem Cells Translational Medicine · 2016 · 441 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17