Plasminogen activator inhibitor-1 promotes immune evasion in tumors by facilitating the expression of programmed cell death-ligand 1 - Concepedia

Concepedia

Publication | Open Access

Plasminogen activator inhibitor-1 promotes immune evasion in tumors by facilitating the expression of programmed cell death-ligand 1

DOI Full Paper Access

32

Citations

38

References

2024

Year

Abd Aziz Ibrahim, Taku Fujimura, Tomoko Uno, Tomoya Terada, Ken‐ichi Hirano, Hiroyuki Hosokawa, Akio Ohta, Toshio Miyata, Kiyoshi Ando, Takashi Yahata

Frontiers in Immunology

Abstract

PAI-1 protects tumors from immune surveillance by increasing PD-L1 expression; hence, therapeutic PAI-1 blockade may prove valuable in treating malignant tumors.

References

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