Concepedia

Publication | Closed Access

ST‐2560, a selective inhibitor of the Na<sub>V</sub>1.7 sodium channel, affects nocifensive and cardiovascular reflexes in non‐human primates

12

Citations

31

References

2024

Year

Abstract

Acute pharmacological inhibition of Na<sub>V</sub>1.7 is antinociceptive, but also has the potential to impact the cardiovascular system. Further work is merited to understand the role of Na<sub>V</sub>1.7 in autonomic ganglia involved in the control of heart rate and blood pressure, and the effect of selective Na<sub>V</sub>1.7 inhibition on cardiovascular function.

References

YearCitations

Page 1