New cyclometalated Ru(<scp>ii</scp>) polypyridyl photosensitizers trigger oncosis in cancer cells by inducing damage to cellular membranes

Abstract

A new generation of benzimidazole-based cyclometalated ruthenium( ii ) complexes with bpy or dpq as ancillary ligands are effective against hypoxic cancers via green light activation and can directly disrupt phospholipid membranes and trigger oncosis.