Concepedia

CoH-catalyzed asymmetric remote hydroalkylation of heterocyclic alkenes: a rapid approach to chiral five-membered S- and O-heterocycles

Lingzi Zhao, Feipeng Liu, Yan Zhuang, Mengyang Shen, Jing Xue, Xuchao Wang, Yuting Zhang, Zi‐Qiang Rong

Chemical Science · 2024 · 10 citations · 121 references

DOIFull text

Open access

Concepts

Abstract

A highly efficient method achieves precise construction of alkyl chiral centers at remote C3-positions in five-membered S/O-heterocycles via cobalt-catalyzed asymmetric remote hydroalkylation of heterocyclic alkenes.

References

121

A Survey of the Role of Noncovalent Sulfur Interactions in Drug Design

Brett R. Beno, Kap‐Sun Yeung, Michael D. Bartberger et al. · Journal of Medicinal Chemistry · 2015 · 766 citations

, , +16

Hydrosilylation reaction of olefins: recent advances and perspectives

Yumiko Nakajima, Shigeru Shimada · RSC Advances · 2015 · 661 citations · Full text

, , +15

Asymmetric Hydrogenation of Heteroaromatic Compounds

Yong‐Gui Zhou · Accounts of Chemical Research · 2007 · 655 citations

, , +16

Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions

Kelsey E. Poremba, Sara E. Dibrell, Sarah E. Reisman · ACS Catalysis · 2020 · 598 citations · Full text

, , +9

Mechanisms of Nickel-Catalyzed Cross-Coupling Reactions

Justin B. Diccianni, Tianning Diao · Trends in Chemistry · 2019 · 594 citations

, , +12