Design, synthesis and molecular docking of 5-fluoro indole derivatives as inhibitors of PI3K/Akt signalling pathway in cervical cancer

Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO Global Cervical Cancer Elimination Initiative

Deependra Singh, Jérôme Vignat, Valentina Lorenzoni et al. · The Lancet Global Health · 2022 · 1.5K citations · Full text

Medicine, Oncology, Population Health Sciences +17

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.

Jin Q. Cheng, Bruce Ruggeri, Willemijn M. Klein et al. · Proceedings of the National Academy of Sciences · 1996 · 793 citations

Medicine, Molecular Biology, Oncology +17

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.

S P Staal · Proceedings of the National Academy of Sciences · 1987 · 770 citations · Full text

Medicine, Molecular Biology, Oncology +17

The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors

Alex Berndt, Simon Miller, Olusegun Williams et al. · Nature Chemical Biology · 2010 · 292 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and antifungal activity of 3-(1,3,4-oxadiazol-5-yl)-indoles and 3-(1,3,4-oxadiazol-5-yl)methyl-indoles

Ming‐Zhi Zhang, Nick Mulholland, David T. Beattie et al. · European Journal of Medicinal Chemistry · 2013 · 152 citations

Pharmacy, Chemistry, Medicinal Chemistry +10