COVID-19: intrapulmonary injection of hydrogen peroxide solution eliminates hypoxia and normalizes respiratory biomechanics

Abstract

Severe SARS is complicated by respiratory obstruction, which is caused by swelling of the mucous membranes of the airways and obstruction of mucus, pus, and thick sputum streaked with blood. A particularly significant decrease in airiness occurs in the peripheral regions of the lungs. This is why the air introduced through the upper respiratory tract does not reach the alveoli, primarily in the peripheral regions of the lungs. Under these conditions, traditional ventilation of the lungs provides a back-and forth movement of air only in the trachea, large and small bronchi, since only these parts of the respiratory tract remain not clogged with mucus and pus. But these parts of the respiratory tract do not provide effective oxygenation of the patient's blood. Therefore, conventional mechanical ventilation (ALV) cannot normalize the biomechanics of breathing until the respiratory obstruction is eliminated. Therefore, with the inhibition of the biomechanics of respiration caused by respiratory obstruction, it is now customary to oxygenate the blood by the extrapulmonary route - using extracorporeal membrane oxygenation (ECMO). However, ECMO is a very dangerous and poorly accessible method of treatment. Therefore, to save the life of patients with severe hypoxia, it is proposed to urgently restore pulmonary oxygenation of the blood by oxygenating the lungs by injecting a solution of a pus solvent into the peripheral regions of the lungs. At the same time, intrapulmonary injection of an alkaline peroxide solvent of pus ensures the immediate appearance of oxygen gas in the peripheral parts of the respiratory tract, since pus and blood veins contain the enzyme catalase, which immediately decomposes hydrogen peroxide into oxygen and water gas. In this case, mucus, pus and sputum streaked with blood immediately turn into oxygen foam, which is easily removed through the upper respiratory tract to the outside.