Concepedia

Favorable impact of PD1/PD-L1 antagonists on bone remodeling: an exploratory prospective clinical study and ex vivo validation

Tamara Gassner, Christina Chittilappilly, Theo Pirich, Benjamin Neuditschko, Klaus Hackner, Judith Lind, Osman Aksoy, Uwe Graichen, Sascha Klee, Franz Herzog,

Journal for ImmunoTherapy of Cancer · 2024 · 11 citations · 48 references

DOIFull text

Open access

Abstract

Our study indicates that the inhibition of the PD1/PD-L1 signaling axis interferes with bone turnover and may exert a protective effect on bone by indirectly promoting osteogenesis.

References

48

Fiji: an open-source platform for biological-image analysis

Johannes Schindelin, Ignacio Arganda‐Carreras, Erwin Frise et al. · Nature Methods · 2012 · 67.6K citations · Full text

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Da Wei Huang, Brad T. Sherman, Richard A. Lempicki · Nature Protocols · 2008 · 36.7K citations

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Cancer statistics, 2022

Rebecca L. Siegel, Kimberly D. Miller, Hannah E. Fuchs et al. · CA A Cancer Journal for Clinicians · 2022 · 17.9K citations · Full text

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The Perseus computational platform for comprehensive analysis of (prote)omics data

Stefka Tyanova, Tikira Temu, Pavel Sinitcyn et al. · Nature Methods · 2016 · 8.5K citations

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The PRIDE database and related tools and resources in 2019: improving support for quantification data

Yasset Pérez‐Riverol, Attila Csordás, Jingwen Bai et al. · Nucleic Acids Research · 2018 · 7.2K citations · Full text

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