Concepedia

Design, synthesis and molecular modeling of novel D-ring substituted steroidal 4,5-dihydropyrazole thiazolinone derivatives as anti-inflammatory agents by inhibition of COX-2/iNOS production and down-regulation of NF-κB/MAPKs in LPS-induced RAW264.7 macrophage cells

Xiaorui Cai, Jianfeng Cai, Ling Fang, Shuopo Fang

European Journal of Medicinal Chemistry · 2024 · 19 citations · 39 references

References

39

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

Oleg Trott, Arthur J. Olson · Journal of Computational Chemistry · 2009 · 37.1K citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties

Guo‐Li Xiong, Jiacai Yi, Li Fu et al. · Nucleic Acids Research · 2021 · 2.7K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Current application of “high-dose” steroid therapy for CNS injury

J. Mark Braughler, Edward D. Hall · Journal of neurosurgery · 1985 · 151 citations

Medicine, Pharmacology, Pharmacotherapy +15

Steroids, non-steroidal anti-inflammatory drugs, and sigmoid diverticular abscess perforation in rheumatic conditions

Shephard Mpofu · Annals of the Rheumatic Diseases · 2004 · 102 citations · Full text

Medicine, Clinical Sciences, Surgery +11

Anti-inflammatory Activity and Mechanism of Surfactin in Lipopolysaccharide-Activated Macrophages

Yuanyuan Zhang, Chuan Liu, Bin Dong et al. · Inflammation · 2014 · 101 citations

Life Sciences, Immunology, Pharmacology +11