A comparative study on prophylactic efficacy of cinnarizine and amitriptyline in childhood migraine: a randomized double-blind clinical trial

Abstract

Both medications are effective in ameliorating migraine headaches and related disabilities. However, amitriptyline appears be a preferable option over cinnarizine, given its faster onset of action, efficacy in reducing headache duration and longer-lasting effects.<b>Trial Registration:</b> The study was registered with the Iranian Registry of Clinical Trials (IRCT) under the code IRCT-20191112045413N1.