Cumulative methotrexate dose is not associated with liver fibrosis in patients with a history of moderate-to-severe psoriasis

Abstract

This study confirms a high prevalence of significant LF in patients with psoriasis. Cumulative methotrexate dose was not associated with LF. Patients with BMI ≥ 28, metabolic syndrome and diabetes are at higher risk for LF. These risk factors may help to identify when a more detailed liver health assessment is needed.