Quantitative Autofluorescence at AMD’s Beginnings Highlights Retinal Topography and Grading System Differences: ALSTAR2 Baseline

Abstract

In a large sample of pseudophakic eyes, qAF8 does not differ overall from normal aging to iAMD but also does not capture the earliest AMD activity in the macula lutea. AREDS classification gives results more consistent with a slow decline in histologic autofluorescence than Beckman classification.