Sonic hedgehog signalling pathway contributes in age-related disorders and Alzheimer's disease

Clinical diagnosis of Alzheimer's disease

Guy M. McKhann, David A. Drachman, Marshall Folstein et al. · Neurology · 1984 · 28K citations · Full text

Medicine, Geriatric Medicine, Neurology +16

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

Yann Echelard, Douglas J. Epstein, Benoit St‐Jacques et al. · Cell · 1993 · 2.2K citations

Life Sciences, Neurobiology, Neuroscience +13

Patched1 Regulates Hedgehog Signaling at the Primary Cilium

Rajat Rohatgi, Ljiljana Milenković, Matthew P. Scott · Science · 2007 · 1.5K citations

Life Sciences, Developmental Biology, Molecular Biology +17

Correlation Between Elevated Levels of Amyloid β-Peptide in the Brain and Cognitive Decline

Jan Näslund · JAMA · 2000 · 1.3K citations

Medicine, Geriatric Medicine, Neurology +12

Increased hippocampal neurogenesis in Alzheimer's disease

Kunlin Jin, Alyson Peel, Xiao Mao et al. · Proceedings of the National Academy of Sciences · 2003 · 976 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17