Concepedia

Recent advances in spirocyclization of maleimides <i>via</i> transition-metal catalyzed C–H activation

Swadhin Swaraj Acharya, Sagarika Patra, Rojalini Maharana, Manaswini Dash, Liza Mama Barad, Bibhuti Bhusan Parida

Organic & Biomolecular Chemistry · 2024 · 43 citations · 50 references

DOI

Concepts

Abstract

C-H activation becomes an important strategy for the synthesis of a diverse array of spirosuccinimides. This review summarizes the reports available in this field from 2015-2023 and also highlights the scopes and prospects of this method.

References

50

C–H activation

Torben Rogge, Nikolaos Kaplaneris, Naoto Chatani et al. · Nature Reviews Methods Primers · 2021 · 616 citations · Full text

Thiol–maleimide “click” chemistry: evaluating the influence of solvent, initiator, and thiol on the reaction mechanism, kinetics, and selectivity

Brian H. Northrop, Stephen H. Frayne, Umesh Choudhary · Polymer Chemistry · 2015 · 241 citations

, , +14

Reversible maleimide–thiol adducts yield glutathione-sensitive poly(ethylene glycol)–heparin hydrogels

Aaron D. Baldwin, Kristi L. Kiick · Polymer Chemistry · 2012 · 175 citations

, , +16

Alkylation, Annulation, and Alkenylation of Organic Molecules with Maleimides by Transition‐Metal‐Catalyzed C‐H Bond Activation

Ramasamy Manoharan, Masilamani Jeganmohan · Asian Journal of Organic Chemistry · 2019 · 156 citations

, , +15

Copper-Mediated Oxidative Coupling of Benzamides with Maleimides via Directed C–H Cleavage

Wataru Miura, Koji Hirano, Masahiro Miura · Organic Letters · 2015 · 150 citations

, , +9