Concepedia

Novel SmartReservoirs for hydrogel-forming microneedles to improve the transdermal delivery of rifampicin

Abraham M. Abraham, Qonita Kurnia Anjani, Masoud Adhami, Aaron R. J. Hutton, Eneko Larrañeta, Ryan F. Donnelly

Journal of Materials Chemistry B · 2024 · 26 citations · 46 references

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Concepts

Abstract

SmartReservoirs (SRs) are novel drug-reservoirs for hydrogel-forming microneedles (HF-MNs). SRs improved rifampicin solubility and diffusion through the HF-matrix, thereby enhancing the transdermal permeation of the poorly soluble antibiotic.

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