Smooth muscle cell-specific matrix metalloproteinase 3 deletion reduces osteogenic transformation and medial artery calcification - Concepedia

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Smooth muscle cell-specific matrix metalloproteinase 3 deletion reduces osteogenic transformation and medial artery calcification

19

Citations

31

References

2024

Year

Yangzhouyun Xie, Tonghui Lin, Ying Jin, Alexa Berezowitz, Xuelin Wang, Jinny Lu, Yujun Cai, Raul J. Guzman

Cardiovascular Research

Abstract

These findings suggest that MMP-3 expression in vascular SMCs is an important regulator of medial calcification and that targeting MMP-3 could provide a therapeutic strategy to reduce it and address its consequences in patients with PAD.

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