Enhanced synthesis of chloramphenicol intermediate L-threo-p-nitrophenylserine using engineered L-threonine transaldolase and by-product elimination

Iron(II)-Catalyzed Intramolecular Aminohydroxylation of Olefins with Functionalized Hydroxylamines

Guansai Liu, Yongqiang Zhang, Yong‐An Yuan et al. · Journal of the American Chemical Society · 2013 · 178 citations

Natural Sciences, Chemistry, Medicinal Chemistry +10

β-Lactone formation during product release from a nonribosomal peptide synthetase

Jason E. Schaffer, Margaret R Reck, Neha Prasad et al. · Nature Chemical Biology · 2017 · 124 citations

Life Sciences, Biochemistry, Molecular Biology +12

An L-threonine transaldolase is required for L-threo-β-hydroxy-α-amino acid assembly during obafluorin biosynthesis

Thomas Allan Scott, Daniel Heine, Zhiwei Qin et al. · Nature Communications · 2017 · 104 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Catalytic Enantio- and Diastereoselective Aldol Reactions of Glycine-Derived Silicon Enolate with Aldehydes:  An Efficient Approach to the Asymmetric Synthesis of <i>anti</i> -β-Hydroxy-α-Amino Acid Derivatives

Jun Kobayashi, Masayuki NAKAMURA, Yuichiro Mori et al. · Journal of the American Chemical Society · 2004 · 73 citations

Natural Sciences, Chemistry, Catalysis +12

Reshaping Substrate-Binding Pocket of Leucine Dehydrogenase for Bidirectionally Accessing Structurally Diverse Substrates

Tao Wu, Yinmiao Wang, Ningxin Zhang et al. · ACS Catalysis · 2022 · 70 citations

Life Sciences, Biochemistry, Molecular Biology +17