Journal of Clinical Medicine · 2024 · 32 citations · 58 references
MedicineDermatologyCosmetic DermatologyDermatopathologyPhotodermatologyHyperpigmentation TreatmentLaser SurgeryMelasma ManagementPigmentary DisordersPigmented Oral LesionsUltraviolet Radiation ProtectionAblative Laser TherapyChemical Peels For MelasmaLaser Therapy For MelasmaMelasma TreatmentMicroneedling For MelasmaPigmentary Disorder TreatmentSkin HyperpigmentationTreatment Safety In Melasma
Melasma is a commonly occurring pigmented skin condition that can significantly affect one's appearance, described as symmetric hyperpigmentation that presents as irregular brown to gray-brown macules on various facial areas, such as the cheeks, forehead, nasal bridge, and upper lip, along with the mandible and upper arms. Due to its complex pathogenesis and recurrent nature, melasma management is challenging and the outcomes following treatment are not always deemed satisfactory. Solely treating hyperpigmentation may prove ineffective unless paired with regenerative techniques and photoprotection, since one of the main reasons for recurrence is sun exposure. Hence, the treatment protocol starts with addressing risk factors, implementing stringent UV protection, and then treatment using different strategies, like applying topical treatments, employing chemical peels, laser and light therapies, microneedling, and systemic therapy. This review aims to provide a summary of the effectiveness and safety of the frequently employed laser and light therapies for treating melasma, focusing on laser therapy as a treatment for melasma.
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Skin responses to fractional photothermolysis
Hans‐Joachim Laubach, Zeina Tannous, R. Rox Anderson et al. · Lasers in Surgery and Medicine · 2006 · 495 citations
Medicine, Dermatology, Pathology +15
A New Formula for Depigmenting Human Skin
Albert M. Kligman · Archives of Dermatology · 1975 · 428 citations