Extracellular ATP contributes to the reactive oxygen species burst and exaggerated mitochondrial damage in D-galactosamine and lipopolysaccharide-induced fulminant hepatitis

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Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

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Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis

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Inflammasome activation leads to Caspase-1–dependent mitochondrial damage and block of mitophagy

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