Concepedia

Oral gepotidacin versus nitrofurantoin in patients with uncomplicated urinary tract infection (EAGLE-2 and EAGLE-3): two randomised, controlled, double-blind, double-dummy, phase 3, non-inferiority trials

Florian Wagenlehner, Caroline Perry, Thomas M. Hooton, Nicole E. Scangarella-Oman, Helen Millns, Marcy Powell, Emily Jarvis, Jeremy Dennison, Amanda Sheets, Deborah Butler,

The Lancet · 2024 · 82 citations · 17 references

DOI

Concepts

References

17

Discrete Sequential Boundaries for Clinical Trials

K. K. Gordon Lan, David L. DeMets · Biometrika · 1983 · 1.7K citations

, , +10

Type IIA topoisomerase inhibition by a new class of antibacterial agents

B.D. Bax, Pan F. Chan, Drake S. Eggleston et al. · Nature · 2010 · 842 citations

, , +13

Randomised controlled trial of nitrofurantoin versus placebo in the treatment of uncomplicated urinary tract infection in adult women.

Thierry C.M. Christiaens, Marc De Meyere, Gerda Verschraegen et al. · PubMed · 2002 · 265 citations · Full text

, , +13

Effect of 5-Day Nitrofurantoin vs Single-Dose Fosfomycin on Clinical Resolution of Uncomplicated Lower Urinary Tract Infection in Women

Angela Huttner, Anna Kowalczyk, ‪Adi Turjeman‬‏ et al. · JAMA · 2018 · 213 citations · Full text

, , +13

Short-Course Nitrofurantoin for the Treatment of Acute Uncomplicated Cystitis in Women

Kalpana Gupta · Archives of Internal Medicine · 2007 · 191 citations

, , +13