Concepedia

Distinct developmental reprogramming footprint of macrophages during acute kidney injury across species

Michal Mrug, Elias Mrug, Frida Rosenblum, Jiandong Chen, Xiangqin Cui, Anupam Agarwal, Abolfazl Zarjou

American Journal of Physiology-Renal Physiology · 2024 · 10 citations · 7 references

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Abstract

Our findings identify robust acute kidney injury (AKI)-induced developmental reprogramming of macrophages (MΦ) with the expansion of C1Q + , CD163 + MΦ that is independent of the etiology of AKI and conserved across mouse and human species.

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