Pentoxifylline protects against cerebral ischaemia-reperfusion injury through ferroptosis regulation via the Nrf2/SLC7A11/GPX4 signalling pathway - Concepedia

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Pentoxifylline protects against cerebral ischaemia-reperfusion injury through ferroptosis regulation via the Nrf2/SLC7A11/GPX4 signalling pathway

DOI Full Paper Access

16

Citations

41

References

2024

Year

Pei Li, Junmin Chen, Shi-Hao Ge, Mei-Lin Sun, Jun-Dong Lu, Fan Liu, Lele Wang, Xin Zhang, Xiaopeng Wang

European Journal of Pharmacology

Abstract

Ferroptosis is evident following cerebral ischaemia-reperfusion in rats. Pentoxifylline confers protection against IRI in rats by inhibiting ferroptosis through the Nrf2/SLC7A11/GPX4 signalling pathway.

References

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