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Secondary Cancers after Chimeric Antigen Receptor T-Cell Therapy
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2024
Year
ImmunologyPathologySecondary CancersCar-t ProductsImmunotherapyOncologyT-cell CancersDiagnostic SciencesRadiation OncologyCancer ResearchMolecular OncologyHealth SciencesCancer PreventionCancer TreatmentMalignant DiseaseCancer ImmunosurveillanceCancer RiskCancer EpidemiologyRare Adverse EventsAdult T-cell Leukemia-lymphomaMedicineCancer Therapeutics
As of December 31, 2023, the FDA had become aware of 22 cases of T-cell cancers that occurred after treatment with CAR-T products. For now, such cancers appear to be relatively rare adverse events.