The immunological landscape of peripheral blood in glioblastoma patients and immunological consequences of age and dexamethasone treatment

Abstract

High-dimensional mass cytometry of peripheral blood in patients with different types of intracranial tumor provides insight into the relation between intracranial pathology and peripheral immune status. Wide immunosuppression associated with age and pre-operative dexamethasone treatment provide further evidence for their deleterious effects on treatment with immunotherapy.