Concepedia

Characterization of Novel Human β-glucocerebrosidase Antibodies for Parkinson’s Disease Research

Tiffany Jong, Alexandra Gehrlein, Ellen Sidransky, Ravi Jagasia, Yu Chen

Journal of Parkinson s Disease · 2024 · 11 citations · 21 references

DOIFull text

Open access

Abstract

The hGCase immunofluorescence, immunoprecipitation, and AlphaLISA assays utilizing hGCase-1/17 and hGCase-1/23 will not only facilitate improved investigations of hGCase biology, but can also serve as tools to assess the distribution and effectiveness of GCase-targeted therapies for PD and related synucleinopathies.

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