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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

On the Experimental Attainment of Optimum Conditions

George E. P. Box, Kerry Wilson · Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1951 · 4.4K citations

Public Health, Mathematics, Experimental Design +4

THE DESIGN OF OPTIMUM MULTIFACTORIAL EXPERIMENTS

R. L. Plackett, J. P. Burman · Biometrika · 1946 · 3.8K citations

Public Health, Decision Sciences, Design Optimization +13

EzTaxon: a web-based tool for the identification of prokaryotes based on 16S ribosomal RNA gene sequences

Jongsik Chun, Jae‐Hak Lee, Yoonyoung Jung et al. · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · 2007 · 2.1K citations

Life Sciences, Bioinformatics, Microbiology +17

A study on the structure–function relationship of lipopeptide biosurfactants

Masaaki Morikawa, Yoshihiko Hirata, Tadayuki Imanaka · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2000 · 607 citations

Life Sciences, Biochemistry, Protein Biochemistry +11