Tick innate immune responses to hematophagy and Ehrlichia infection at single-cell resolution

Abstract

Our results uncover the tick immune responses to <i>Ehrlichia</i> infection and hematophagy at a single-cell resolution. This work opens a new field of tick innate immunobiology to understand the role of hemocytes, particularly in response to prolonged blood-feeding (hematophagy), and tick-microbial interactions.