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Publication | Open Access

The IRF1/GBP5 axis promotes osteoarthritis progression by activating chondrocyte pyroptosis

29

Citations

29

References

2023

Year

Abstract

This study underscores the significance of the IRF1/GBP5 axis in NLRP3 inflammasome-mediated chondrocyte pyroptosis and osteoarthritic chondrocyte injury. Modulating IRF1 and GBP5 expression could serve as a novel therapeutic target for OA.

References

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