Concepedia

Fetuin B in white adipose tissue induces inflammation and is associated with peripheral insulin resistance in mice and humans

Kenneth Pasmans, Gijs H. Goossens, Evi Groenhuijzen, Esther J Kemper, Dorien Reijnders, Jasper Most, Ellen E. Blaak, Matthew J. Watt, Ruth C. R. Meex

Obesity · 2023 · 15 citations · 17 references

DOIFull text

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Abstract

Fetuin B content in white adipose tissue strongly associated with peripheral insulin resistance in mice and humans. Furthermore, fetuin B induced a proinflammatory response in adipocytes, which might drive peripheral insulin resistance.

References

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Tissue distribution and activity testing suggest a similar but not identical function of fetuin-B and fetuin-A

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