Single‐cell sequencing identifies inflammation‐promoting fibroblast–neutrophil interaction in peri‐implantitis

Abstract

Our study indicated that the predominance of CXCL8⁺ fibroblast-CXCR2⁺ neutrophil interaction might underline the enhanced host response in peri-implantitis compared with periodontitis. This information offers a molecular basis by which fibroblast and neutrophil subtypes might be diagnostically and therapeutically targeted in peri-implantitis.