Publication | Open Access
Targeting MMP9 in CTNNB1 mutant hepatocellular carcinoma restores CD8 <sup>+</sup> T cell-mediated antitumour immunity and improves anti-PD-1 efficacy
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Citations
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References
2023
Year
CTNNB1 <i><sup>GOF</sup></i> induces a suppressive TIME by activating secretion of MMP9. Targeting MMP9 reshapes TIME and potentiates anti-PD-1 efficacy in CTNNB1 <i><sup>GOF</sup></i> HCC.
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