New triazole-based coordination complexes as antitumor agents against triple negative breast cancer MDA-MB-468 cell line

Youssef Draoui, Smaail Radi, Yousra Bahjou, Abderrazak Idir, Amal El Mahdaoui, Abdelmajid Zyad, Haralampos N. Miras, Marilena Ferbinţeanu, Aurelian Rotaru, Yann Garcia

RSC Advances · 2023 · 11 citations · 33 references

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Abstract

(4), for which the crystal structure was earlier determined. Notably, cadmium complexes 3 and 7 exhibit remarkable cytotoxicity and demonstrated a high selectivity index towards cancer cells when compared to peripheral blood mononuclear cells. Such activity highlights their potential function as anticancer agents.

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