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Publication | Open Access

Hepatitis D infection induces IFN-β-mediated NK cell activation and TRAIL-dependent cytotoxicity

DOIFull Paper Access

11

Citations

52

References

2023

Year

Christopher Groth, Jovana Marić, Irene Garcés Lázaro, Tomáš Hofman, Zhenfeng Zhang, Yi Ni, Franziska Maria Keller, Isabelle Seufert, Maike Hofmann, Christoph Neumann‐Haefelin,
Frontiers in Immunology

Abstract

Our data demonstrate NK cell activation in HDV infection and their potential to eliminate HDV-infected hepatoma cells via the TRAIL/TRAIL-R2 axis which implies a high relevance of NK cells for the design of novel anti-viral therapies.

References

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