Concepedia

The anticancer application of half-sandwich iridium(<scp>iii</scp>) ferrocene-thiosemicarbazide Schiff base complexes

Xicheng Liu, Ao Lv, Pei Zhang, Jiaying Chang, Ruixiao Dong, Mengxian Liu, Jiayi Liu, Xiaoqing Huang, Xiang‐Ai Yuan, Zhe Liu

Dalton Transactions · 2023 · 19 citations · 55 references

DOI

Concepts

Abstract

toxicity assays confirmed that these complexes showed better anti-migration ability and less toxicity in comparison to cisplatin. Thus, these complexes provide a new strategy for the design of non-platinum organometallic anticancer drugs.

References

55

Application of ferrocene and its derivatives in cancer research

Cátia Ornelas · New Journal of Chemistry · 2011 · 471 citations

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Organometallic Half-Sandwich Iridium Anticancer Complexes

Zhe Liu, Abraha Habtemariam, Ana M. Pizarro et al. · Journal of Medicinal Chemistry · 2011 · 353 citations · Full text

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Ferroptosis Photoinduced by New Cyclometalated Iridium(III) Complexes and Its Synergism with Apoptosis in Tumor Cell Inhibition

Hao Yuan, Zhong Han, Yuncong Chen et al. · Angewandte Chemie International Edition · 2021 · 272 citations

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Ruthenium Polypyridyl Complexes That Induce Mitochondria-Mediated Apoptosis in Cancer Cells

Tianfeng Chen, Yanan Liu, Wenjie Zheng et al. · Inorganic Chemistry · 2010 · 244 citations

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A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability

Hana Antonická, Karine Choquet, Zhen‐Yuan Lin et al. · EMBO Reports · 2016 · 190 citations · Full text

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