Bacteroides vulgatus alleviates dextran sodium sulfate-induced colitis and depression-like behaviour by facilitating gut-brain axis balance

Abstract

<i>B. vulgatus</i> and <i>B. vulgatus</i>-derived 4-HPAA ameliorated intestinal inflammation and relieved depressive symptoms through the gut-brain axis. Thus, administration of <i>B. vulgatus</i> or 4-HPAA supplementation is a promising therapeutic strategy for treating IBD, particularly IBDD.