A single-component, light-assisted uncaging switch for endoproteolytic release

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

Manfred Gossen, Heidelberg Bujard · Proceedings of the National Academy of Sciences · 1992 · 5K citations

Life Sciences, Genetics, Molecular Biology +17

Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency

Rachel B. Kapust, József Tőzsér, Jeffrey D. Fox et al. · Protein Engineering Design and Selection · 2001 · 879 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins

Gurkan Guntas, Ryan A. Hallett, Seth P. Zimmerman et al. · Proceedings of the National Academy of Sciences · 2014 · 704 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells

J Berger, Joachim Hauber, Regina Hauber et al. · Gene · 1988 · 682 citations

Life Sciences, Genetics, Molecular Biology +8

Posttranslational N-Myristoylation of BID as a Molecular Switch for Targeting Mitochondria and Apoptosis

Jiping Zha, Solly Weiler, Kyoung Joon Oh et al. · Science · 2000 · 555 citations

Life Sciences, Biochemistry, Molecular Biology +17